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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist known for its robust systemic antitumor efficacy. It has demonstrated superior antitumor activity in in-vivo studies, specifically in mice bearing bilateral B16-OVA melanomas with a 10 μg intra-tumoral injection.
Highly potent cyclic dinucleotide STING agonist
Robust systemic antitumor efficacy
Molecular weight: 726.60
Molecular formula: C20H29FN12O9P2S2
Appearance: Solid
Color: White to off-white
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Amfenac Sodium Monohydrate (CAS 61618-27-7) is a synthetic non-steroidal anti-inflammatory compound structurally characterized by an acetic acid moiety It functions by inhibiting cyclooxygenase (COX) enzymes consequently suppressing prostaglandin synthesis and mitigating inflammatory processes and pain signaling Amfenac Sodium Monohydrate is utilized in biomedical research to investigate inflammatory pathways and to evaluate non-steroidal analgesic drug effects in cellular and animal models of inflammation Its well-defined inhibitory mechanism makes it a valuable tool for elucidating COX-mediated physiological and pathological responses
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HO-PEG-CH2COOH (MW 35,000) is a carboxy-terminated polyethylene glycol (PEG) polymer used as a hydrophilic spacer for PROTAC synthesis and other bioconjugation applications. The polymer features a hydroxyl terminus and a carboxymethyl terminus, providing a reactive carboxylic acid for coupling chemistries. Supplied as a white to off-white solid with ~95.0% purity; recommended storage is -20°C under nitrogen.
High molecular weight PEG spacer (35,000 Da) for increased solubility and linker length.
Carboxy-terminated for straightforward amide or ester coupling.
Hydroxyl-terminated opposite end for orthogonal functionalization.
Solid powder form is easy to handle and weigh for synthesis workflows.
Stable under recommended storage; in solvent store at -80°C for extended stability.
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